Chapter II · Supplement · Advanced Therapy
Spravato® (Esketamine) Treatment in Omaha, NE
Spravato (esketamine) is an FDA-approved nasal spray medication used alongside an oral antidepressant for treatment-resistant depression and for depressive symptoms in adults with suicidal thoughts or actions. It's administered only in a certified, monitored clinical setting, never taken home, under an FDA Risk Evaluation and Mitigation Strategy (REMS) program.
When the Pills Haven't Worked
If you've tried medication after medication and still don't feel like yourself, you already know the frustration of "just give it more time." Treatment-resistant depression isn't a lack of effort on your part. It's a sign your brain may need a different kind of intervention.
Spravato works differently than a daily pill, and for many people, it's the first thing that's actually moved the needle.
Treatment-resistant depression isn't a lack of effort on your part.
Why Felina

Spravato is a serious medication that requires serious oversight, which is exactly the environment we've built. As a psychiatric nurse practitioner with over 25 years of clinical experience, including both acute and psychiatric care, Felina doesn't just prescribe Spravato. She personally evaluates whether it's the right fit for you, walks you through what to expect, and stays involved in your care as your treatment progresses. You're not handed off to a rotating clinical staff for monitoring visits; your treatment plan reflects a provider who has seen how this medication performs across a wide range of real patients, including the more complex cases (comorbid PTSD, OCD, or anxiety alongside depression) where a less experienced provider might not know how to adjust course.
The Course of Care
What treatment looks like at Verve Collaborative Health in Omaha
Everything begins with an initial evaluation and full psychiatric assessment with Felina to determine if Spravato is appropriate, including a review of risk factors and contraindications. If Spravato is clinically indicated and appropriate, treatment follows a structured rhythm:
Education first
A full discussion of the treatment itself before anything starts: what it is, how it works, and what to expect.
In-office dosing sessions
Typically twice weekly to begin, in our dedicated Spravato treatment clinic.
Supervised monitoring
Each session requires about two hours in-clinic, with supervised monitoring of blood pressure and vital signs.
Tapering over time
Session frequency is tapered down over time based on your clinical response.
Support between visits
Alongside Spravato sessions, we recommend guided journaling to track mood shifts, regular therapy sessions to build on the work Spravato supports, and consistent follow-up with Felina to keep your treatment progressing as expected.
Please plan ahead: patients must arrange a driver, as you cannot drive yourself home the day of treatment. Exact dosing schedules vary by patient and are determined individually.
Off-label use for comorbid conditions. Spravato is FDA-approved specifically for treatment-resistant depression and for depression with suicidal thoughts or actions. In select cases involving major depressive disorder with comorbid PTSD, OCD, or anxiety, Spravato may be used off-label, based on clinical trial data and results observed in practice. This is not an FDA-approved indication, and outcomes vary by patient. Felina will discuss whether this may be appropriate for your specific diagnosis during your evaluation.
Spravato Facts
Questions patients ask most
What is Spravato and how does it work?
Spravato (esketamine) is an FDA-approved nasal spray medication used alongside an oral antidepressant for treatment-resistant depression and for depressive symptoms in adults with suicidal thoughts or actions. It works differently than a daily pill, and it is administered only in a certified, monitored clinical setting, never taken home, under an FDA Risk Evaluation and Mitigation Strategy (REMS) program.
Who is Spravato for?
Spravato is FDA-approved for treatment-resistant depression (when you've tried multiple antidepressants without real relief) and for depressive symptoms in adults with suicidal thoughts or actions. Whether it's appropriate for you is determined at an initial evaluation and full psychiatric assessment with Felina, including a review of risk factors and contraindications.
What happens during a treatment session?
Dosing happens in our dedicated Spravato treatment clinic, typically twice weekly to start. Each session requires about two hours in-clinic with supervised monitoring of blood pressure and vital signs. Session frequency is tapered down over time based on your clinical response.
Can I drive myself home after a session?
No. Patients must arrange a driver; you cannot drive yourself home the day of treatment.
How often will I need treatments?
Sessions are typically twice weekly at the start, with frequency tapered down over time based on clinical response. Exact dosing schedules vary by patient and are determined individually, so they aren't listed here.
Do you accept insurance for Spravato?
Spravato treatment requires insurance authorization prior to starting. We are currently unable to accept Medicare or Medicaid for Spravato specifically. Our team will verify your coverage and discuss any cost details with you before treatment begins.
Where in Omaha are Spravato treatment sessions held?
Sessions are held in our dedicated Spravato treatment clinic at Verve Collaborative Health, 11404 West Dodge Road, Suite 300, Omaha, NE 68154, where Elaion Mental Health, PLLC at Verve Collaborative Health operates. We serve patients from Omaha and the surrounding metro, including Bellevue, Papillion, La Vista, Elkhorn, and Council Bluffs. Consultations and scheduling go through Verve Collaborative Health.
Can Spravato help with PTSD, OCD, or anxiety alongside depression?
Spravato is FDA-approved specifically for treatment-resistant depression and for depression with suicidal thoughts or actions. In select cases involving major depressive disorder with comorbid PTSD, OCD, or anxiety, Spravato may be used off-label, based on clinical trial data and results observed in practice. This is not an FDA-approved indication, and outcomes vary by patient. Felina will discuss whether this may be appropriate for your specific diagnosis during your evaluation.
Official Documentation
Patient documents to download and keep
These are the official Spravato® documents from Janssen Pharmaceuticals, provided here for your records. The Patient Brochure is the easiest overview to start with; the Medication Guide is the FDA-required safety summary to read before your first session.
- Download ↓
Spravato Patient Brochure
The friendliest place to start: Janssen's illustrated patient brochure covering what Spravato is, what treatment days look like, side effects, and cost support.
- Download ↓
Spravato Medication Guide
The FDA-required patient guide: the most important safety information, side effects to watch for, and what to avoid on treatment days.
- Download ↓
Full Prescribing Information
The complete FDA-approved labeling for patients who want every detail: indications, REMS program requirements, dosing, warnings, and clinical trial data.
Documents are reproduced from the manufacturer's current official labeling. The latest versions are always available atspravato.comandspravatorems.com.
Getting Started
Consultations are scheduled through Verve Collaborative Health, where Elaion Mental Health operates.
Schedule at Verve Collaborative →View on Psychology Today →
Serving Omaha and the surrounding metro, including Bellevue, Papillion, La Vista, Elkhorn, and Council Bluffs.
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Mental Health · Felina Sno, Vol. I · Omaha, Nebraska


